Staphopains modulate Staphylococcus aureus biofilm integrity

…Staphylococcus aureus is a known cause of chronic biofilm infections that can reside on medical implants or host tissue. Recent studies have demonstrated an important role for proteinaceous material in the biofilm structure. The S. aureus genome encodes many secreted proteases, and there is growing evidence that these enzymes have self-cleavage properties that alter biofilm integrity. …sent for the production of chicken antibodies to ScpA (Pacific Immunology)…
Joe M. Mootz1, Cheryl L. Malone1, Lindsey N. Shaw2 and Alexander R. Horswill
ASM Infection and Immunity 24 June 2013, doi: 10.1128/IAI.00377-13

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