Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina

… Equilibrium isomerization of retinol is a new activity now attributable to DES1. 11-cis-retinol synthesized by DES1 in Müller cells of the retina can be converted to the visual chromophore for regenerating opsin pigment in cone photoreceptors…
JJ Kaylor, Q Yuan, J Cook, S Sarfare, J Makshanoff… –
Nature Chemical Biology, 2012

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