EscE and EscG are co-chaperones for the type III needle protein EscF of enteropathogenic E. coli

…Type III secretion systems (T3SS) are central virulence mechanisms used by a variety of Gram-negative bacteria to inject effector proteins into host cells. The needle polymer is an essential part of the T3SS that provides the effector proteins a continuous channel into the host cytoplasm…
Neta Sal-Man1, Dheva Setiaputra1, Roland Scholz1, Wanyin Deng1, Angel C.Y. Yu2,4, Natalie C.J. Strynadka2,4 and B. Brett Finlay1,2,3,*
Journal of Bacteriology March 2013, doi: 10.1128/JB.00118-13

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