Activated Cdc42 kinase regulates Dock localization in male germ cells during Drosophila spermatogenesis

…Deregulation of the non-receptor tyrosine kinase ACK1 (Activated Cdc42-associated kinase) correlates with poor prognosis in cancers and has been implicated in promoting metastasis. To further understand its in vivo function, we have characterized the developmental defects of a null mutation in Drosophila Ack, which bears a high degree of sequence similarity to…
Abbas M. Abdallah, Xin Zhou, Christine Kim, Kushani K. Shah, Christopher Hogden, Jessica A. Schoenherr, James C. Clemens, Henry C. Chang
Developmental Biology Volume 378, Issue 2, 15 June 2013, Pages 141–153

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